Publications

 

2015 M Boerries, R Herr, T Brummer, H Busch Global gene expression profiling analysis reveals reduction of stemness after B-RAF inhibition in colorectal cancer cell lines. Genomics Data 4, 158-161
Theresa D Ahrens, Sylvia Timme, Jens Hoeppner, Jenny Ostendorp, Sina Hembach, Marie Follo, Ulrich T Hopt, Martin Werner, Hauke Busch, Melanie Boerries, Silke Lassmann Selective inhibition of esophageal cancer cells by combination of HDAC inhibitors and Azacytidine Epigenetics 10, 431-445
S Koszinowski, M Boerries, H Busch, K Krieglstein RARβ regulates neuronal cell death and differentiation in the avian ciliary ganglion Developmental Neurobiology, 2015 doi: 10.1002/dneu.22278
2014 Grahammer, F., Haenisch, N., Steinhardt, F., Sander, L., Roerden, M., Arnold, F., Cordts, T., Wanner, N., Reichardt, W., Kerjaschki, D., et al. mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress. PNAS 111, E2817–E2826.
PNAS
Rohde, D., Schön, C., Boerries, M., Didrihsone, I., Ritterhoff, J., Kubatzky, K.F., Völkers, M., Herzog, N., Mähler, M., Tsoporis, J.N., et al. ‘S100A1 is released from ischemic cardiomyocytes and signals myocardial damage via Toll-like receptor 4’. EMBO Mol Med.
Pubmed 24833748
Ebeling, S., Naumann, K., Pollok, S., Wardecki, T., Vidal-y-Sy, S., Nascimento, J.M., Boerries, M., Schmidt, G., Brandner, J.M., and Merfort, I. (2014). From a Traditional Medicinal Plant to a Rational Drug: Understanding the Clinically Proven Wound Healing Efficacy of Birch Bark Extract. PLoS ONE 9, e86147.
Pubmed 24465925
Kalfalah, F., Sobek, S., Bornholz, B., Götz-Rösch, C., Tigges, J., Fritsche, E., Krutmann, J., Körer, K., Deenen, R., Ohse, S., et al. Inadequate mito-biogenesis in primary dermal fibroblasts from old humans is associated with impairment of PGC1A-independent stimulation. Experimental Gerontology. Download
2013 Neumann J., Boerries M., Köhler R., Giaisi M., Krammer P., Busch H., Li-Weber M, ‘The natural anticancer compound rocaglamide selectively inhibits the G1-S-phase transition in cancer cells through the ATM/ATR-mediated Chk1/2 cell cycle checkpoints.’ Int J Cancer 2013, doi: 10.1002/ijc.28521 Pubmed 24150948
Timme S, Ihde S, Fichter CD, Waehle V, Bogatyreva L, Atanasov K, Kohler I, Schöpflin A, Geddert H, Faller G, Klimstra D, Tang L, Reinheckel T, Hauschke D, Busch H, Boerries M, Werner M, Lassmann S. STAT3 expression, activity and functional consequences of STAT3 inhibition in esophageal squamous cell carcinomas and Barrett’s adenocarcinomas. Oncogene. 2013 Aug 5. doi: 10.1038/onc.2013.298. Pubmed 23912451
Buck, M., Saltukoglu, D., Boerries, M., Simons, M., and Busch, H. (2013). A distributed stochastic perception-action loop model of cell motility. In 2013 IEEE Symposium on Artificial Life (ALIFE), pp. 5–12. Download
Sprenger A, Weber S, Zarei M, Engelke R, Nascimento JM, Gretzmeier C, Hilpert M, Boerries M, Has C, Busch H, Bruckner-Tuderman L, Dengjel J. Consistency of the proteome in primary human keratinocytes with respect to gender, age, and skin localization. Mol Cell Proteomics. 2013 May 30. Pubmed 23722187
Busch H, Boerries M, Bao J, Hanke ST, Hiss M, Tiko T, Rensing SA.Network theory inspired analysis of time-resolved expression data reveals key players guiding P. patens stem cell development. PLoS One. 2013 Apr 18;8(4):e60494. doi: 10.1371/journal.pone.0060494. Print 2013. Pubmed 23637751
Küttner V, Mack C, Rigbolt KT, Kern JS, Schilling O, Busch H, Bruckner-Tuderman L, Dengjel J. Global remodelling of cellular microenvironment due to loss of collagen VII. Mol Syst Biol. 2013 Apr 16;9:657. doi: 10.1038/msb.2013.17. Pubmed 23591773
Weber S, Fernández-Cachón ML, Nascimento JM, Knauer S, Offermann B, Murphy RF, Boerries M, Busch H. Label-free detection of neuronal differentiation in cell populations using high-throughput live-cell imaging of PC12 cells. PLoS One. 2013;8(2):e56690. doi: 10.1371/journal.pone.0056690. Epub 2013 Feb 22. Pubmed 23451069
Boerries M, Grahammer F, Eiselein S, Buck M, Meyer C, Goedel M, Bechtel W, Zschiedrich S, Pfeifer D, Laloë D, Arrondel C, Gonçalves S, Krüger M, Harvey SJ, Busch H, Dengjel J, Huber TB. Molecular fingerprinting of the podocyte reveals novel gene and protein regulatory networks. Kidney Int. 2013 Jan 30. doi: 10.1038/ki.2012.487. [Epub ahead of print] PMID: 23364521 Pubmed 23364521
Tholen S, Biniossek ML, Gansz M, Gomez-Auli A, Werner F, Noel A, Kizhakkedathu JN, Boerries M, Busch H, Reinheckel T, Schilling O.Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome. Mol Cell Proteomics. 2013 Mar;12(3):611-25. doi: 10.1074/mcp.M112.017962. Epub 2012 Dec 10.Pubmed 23233448
2012 Singh A, Nascimento JM, Kowar S, Busch H, Boerries M.Boolean approach to signalling pathway modelling in HGF-induced keratinocyte migration. Bioinformatics. 2012 Sep 15;28(18):i495-i501. doi: 10.1093/bioinformatics/bts410. Pubmed 22962472
2011 Bachmann J, Raue A, Schilling M, Böhm ME, Kreutz C, Kaschek D, Busch H, Gretz N, Lehmann WD, Timmer J, Klingmüller U. . Division of labor by dual feedback regulators controls JAK2/STAT5 signaling over broad ligand range. Mol Syst Biol. 2011 Jul 19;7:516. doi: 10.1038/msb.2011.50. Pubmed 21772264
Mesecke S, Urlaub D, Busch H, Eils R, Watzl C. Integration of activating and inhibitory receptor signaling by regulated phosphorylation of Vav1 in immune cells. Sci Signal. 2011 May 31;4(175):ra36. doi: 10.1126/scisignal.2001325. Pubmed 21632469
Bhattacharya N, Diener S, Idler IS, Rauen J, Häbe S, Busch H, Habermann A, Zenz T, Döhner H, Stilgenbauer S, Mertens D. Nurse-like cells show deregulated expression of genes involved in immunocompetence. Br J Haematol. 2011 Aug;154(3):349-56. doi: 10.1111/j.1365-2141.2011.08747.x. Epub 2011 May 25.Pubmed 21615384
Heinemann A, He Y, Zimina E, Boerries M, Busch H, Chmel N, Kurz T, Bruckner-Tuderman L, Has C. Induction of phenotype modifying cytokines by FERMT1 mutations. Hum Mutat. 2011 Apr;32(4):397-406. doi: 10.1002/humu.21449. Epub 2011 Mar 1. Pubmed 21309038
2010 Maiwald T, Schneider A, Busch H, Sahle S, Gretz N, Weiss TS, Kummer U, Klingmüller U. Combining theoretical analysis and experimental data generation reveals IRF9 as a crucial factor for accelerating interferon α-induced early antiviral signalling. FEBS J. 2010 Nov;277(22):4741-54. doi: 10.1111/j.1742-4658.2010.07880.x. Epub 2010 Oct 21. Pubmed20964804
Sprenger A, Küttner V, Biniossek ML, Gretzmeier C, Boerries M, Mack C, Has C, Bruckner-Tuderman L, Dengjel J. Comparative quantitation of proteome alterations induced by aging or immortalization in primary human fibroblasts and keratinocytes for clinical applications. Mol Biosyst. 2010 Sep;6(9):1579-82. doi: 10.1039/c003962d. Epub 2010 May 10. Pubmed20454738
2009 Kraus C, Rohde D, Weidenhammer C, Qiu G, Pleger ST, Voelkers M, Boerries M, Remppis A, Katus HA, Most P. S100A1 in cardiovascular health and disease: closing the gap between basic science and clinical therapy. J Mol Cell Cardiol. 2009 Oct;47(4):445-55. doi: 10.1016/j.yjmcc.2009.06.003. Epub 2009 Jun 16. Review.Pubmed19538970
2008 Busch H, Camacho-Trullio D, Rogon Z, Breuhahn K, Angel P, Eils R, Szabowski A. Gene network dynamics controlling keratinocyte migration. Mol Syst Biol. 2008;4:199. doi: 10.1038/msb.2008.36. Epub 2008 Jul 1. Pubmed 18594517
2007 Boerries M, Most P, Gledhill JR, Walker JE, Katus HA, Koch WJ, Aebi U, Schoenenberger CA. Ca2+ -dependent interaction of S100A1 with F1-ATPase leads to an increased ATP content in cardiomyocytes.Mol Cell Biol. 2007 Jun;27(12):4365-73. Epub 2007 Apr 16.Pubmed17438143
2006 Glatt E, Busch H, Kaiser F, Zaikin A. Noise-memory induced excitability and pattern formation in oscillatory neural models. Phys Rev E Stat Nonlin Soft Matter Phys. 2006 Feb;73(2 Pt 2):026216. Epub 2006 Feb 22. Pubmed 16605438
2005 H. Busch, R. Eils. Systems Biology, in Encyclopedia of Molecular Cell Biology and Molecular Medicine, 14, 123, (2005)
Most P, Boerries M, Eicher C, Schweda C, Völkers M, Wedel T, Söllner S, Katus HA, Remppis A, Aebi U, Koch WJ, Schoenenberger CA.Distinct subcellular location of the Ca2+-binding protein S100A1 differentially modulates Ca2+-cycling in ventricular rat cardiomyocytes. J Cell Sci. 2005 Jan 15;118(Pt 2):421-31.Pubmed 15654019
2004 Most P, Pleger ST, Völkers M, Heidt B, Boerries M, Weichenhan D, Löffler E, Janssen PM, Eckhart AD, Martini J, Williams ML, Katus HA, Remppis A, Koch WJ. Cardiac adenoviral S100A1 gene delivery rescues failing myocardium. J Clin Invest. 2004 Dec;114(11):1550-63.Pubmed 15578088
H. Busch and M.-Th. Hütt. Scale-dependence of spatiotemporal filters inspired by cellular automata. Int. J. Bifurcation Chaos, 14, 1957, (2004)
2003 H. Busch, J. Garcia-Ojalvo, and F. Kaiser. Influence of spatiotemporal 1/f -noise on structure formation in excitable media. Proc. SPIE, 5114, 468, (2003).
Most P, Boerries M, Eicher C, Schweda C, Ehlermann P, Pleger ST, Loeffler E, Koch WJ, Katus HA, Schoenenberger CA, Remppis A.Extracellular S100A1 protein inhibits apoptosis in ventricular cardiomyocytes via activation of the extracellular signal-regulated protein kinase 1/2 (ERK1/2). J Biol Chem. 2003 Nov 28;278(48):48404-12. Epub 2003 Sep 6. Pubmed 12960148
Busch H, Kaiser F. Influence of spatiotemporally correlated noise on structure formation in excitable media. Phys Rev E Stat Nonlin Soft Matter Phys. 2003 Apr;67(4 Pt 1):041105. Epub 2003 Apr 25.Pubmed 12786345