Oberseminar WS 18/19: High-Throughput Methods in Life Science

Oberseminar WS 18/19: High-Throughput Methods in Life Science

High-throughput methods allow the simultaneous measurement of many cellular variables, such as protein content, gene expression or cell state. They have become an integrated part of current biological research to unravel the complexity of living systems and technology is advancing at a rapid pace. This seminar is aimed at presenting the latest methods in proteomics, genomics and deep sequencing, as well as strategies to turn this data into new discoveries in biology and treatments in medicine.

Dozenten:

Dr. Dr. Melanie Boerries
Dr. Hans Gmuender
Dr. Arnd Brandenburg

Registration via Email e-mail an m.boerries@dkfz.de

First meeting: Monday, October 15th 2018, 13:00ct, Seminarraum ZBSA

Seminar time: tba, Seminar room of the ZBSA

The Oberseminar and all talks will be presented in English.

    • Topic: Neoepitopes as cancer immunotherapy targets
    • Literature: Brennick et al.
    • Supervisor: Arnd Brandenburg/Hans Gmuender
    • Topic: The Principles of Engineering Immune Cells to Treat Cancer
    • Literature: Lim et al.
    • Supervisor: Arnd Brandenburg/Hans Gmuender
    • Topic: Applications of Immunogenomics to Cancer
    • Literature: Liu, Mardis et al.
    • Supervisor: Arnd Brandenburg/Hans Gmuender
    • Topic: Gene Regulatory Network Analysis Identifies
      Sex-Linked Differences in Colon Cancer Drug
      Metabolism
    • Literature: Lopes-Ramos
    • Supervisor: Melanie Boerries
    • Topic: An RNA toolbox for cancer immunotherapy
    • Literature: Pastor et al.
    • Supervisor: Arnd Brandenburg/Hans Gmuender
    • Topic: Application of scRNA-seq in human cancer
    • Literature: Rantalainan et al.
    • Supervisor: Arnd Brandenburg/Hans Gmuender
    • Topic: A Paradigm Shift in Cancer Immunotherapy From Enhancement to Normalization
    • Literature:Sanmamed, Chen et al.
    • Supervisor: Arnd Brandenburg/Hans Gmuender
    • Topic: Neoepitopes of Cancers Looking Back, Looking Ahead
    • Literature: Srivastava et al.
    • Supervisor: Arnd Brandenburg/Hans Gmuender
    • Topic: Personalized vaccines for cancer immunotherapy
    • Literature: Sahin, Tuereci et al.
    • Supervisor: Arnd Brandenburg/Hans Gmuender
    • Topic: Biophysical properties of the clinical-stage antibody landscape
    • Literature: Jain et al.
    • Supervisor: Arnd Brandenburg/Hans Gmuender
    • Topic: Evolutionary routes and KRAS dosage define pancreatic cancer phenotypes
    • Literature: Mueller et al.
    • Supervisor: Melanie Boerries
    • Topic: Understanding Tissue-Specific Gene Regulation
    • Literature: Sonawane et al.
    • Supervisor: Melanie Boerries
    • Topic: Tumor and Microenvironment Evolution
      during Immunotherapy with Nivolumab
    • Literature: Riaz et al
    • Supervisor: Melanie Börries